Three years into the implementation of the 2030 Agenda, Latin America and the Caribbean face great challenges. More than half of the countries in the region have national coordination mechanisms for the implementation and follow-up of this Agenda. Most of these mechanisms have entrusted planning institutions with the role of coordinator or technical secretariat for coordinating the various sectors, convening stakeholders and defining the strategies and partnerships for achieving the Sustainable Development Goals (SDGs) as well as monitoring and ensuring accountability of the Goals. This methodological guide from the Economic Commission for Latin America and the Caribbean (ECLAC) is intended to provide conceptual and practical inputs that enable countries to formulate strategies —whether at the national or subnational level— for the implementation of the 2030 Agenda.