This document examines the situation of persons with disabilities, in terms of the impact that COVID-19 could have, taking into consideration age and sex, health conditions, types of disability, access to basic infrastructure, overcrowding in the home, access to information and communications technology (ICT), employment status and education. In conclusion, the report presents some national actions that have been taken to reduce the impact of the pandemic and recommendations for addressing the devastating social and economic effects of COVID-19 on persons with disabilities.