The 2022 edition of the Demographic Observatory offers selected indicators of population estimates and projections for 38 countries and territories in Latin America and the Caribbean. The estimates and projections were prepared by CELADE in conjunction with the United Nations Population Division (UNPD) for the 20 countries of Latin America; those for the 18 Caribbean countries and territories were prepared by UNPD. This new release updates previously published figures and uses the cohort component method by single ages and calendar years, unlike the 2019 edition, which was prepared for years ending in 0 and 5 and for age groups. The data for national population estimates and projections for the countries of Latin America and the Caribbean is available on the ECLAC website (https://www.cepal.org/en/subtopics/demographic-projections/latin-america-and-caribbean-population-estimates-and-projections).The figures included in this edition of the Demographic Observatory, as well as the eight variant population projections prepared by the United Nations Population Division, are available on the Division’s website (https://population.un.org/wpp/).